GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs428445 | 1 | rs4811694 | chr20:55029388 | C20orf43 | chr20:55043647-55093942:+ | 0.3 | 8.09 | 5.03E-15 | Refractive astigmatism |
| THCA | cis | rs4812048 | 1 | rs4812048 | chr20:57587771 | TH1L | chr20:57556311-57570186:+ | -0.18 | -4.3 | 2.06E-5 | Mean platelet volume |
| THCA | cis | rs4813003 | 1 | rs4813001 | chr20:44762857 | CD40 | chr20:44746906-44758384:+ | -0.19 | -3.6 | 0.000346 | Kawasaki disease |
| THCA | cis | rs4813003 | 1 | rs4813002 | chr20:44763187 | CD40 | chr20:44746906-44758384:+ | -0.19 | -3.73 | 0.000211 | Kawasaki disease |
| THCA | cis | rs4813003 | 1 | rs4813003 | chr20:44763284 | CD40 | chr20:44746906-44758384:+ | -0.2 | -3.8 | 0.000165 | Kawasaki disease |
| THCA | cis | rs7267979 | 1 | rs4813562 | chr20:25352588 | ENTPD6 | chr20:25176339-25207360:+ | 0.32 | 7.23 | 1.88E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4813562 | chr20:25352588 | FAM182A | chr20:26035250-26067552:+ | 0.19 | 3.49 | 0.000536 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4813562 | chr20:25352588 | FAM182B | chr20:25744102-25848786:- | -0.26 | -5.4 | 1.06E-7 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4813562 | chr20:25352588 | NINL | chr20:25433338-25566153:- | 0.33 | 6.9 | 1.7E-11 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4813562 | chr20:25352588 | PYGB | chr20:25228706-25278647:+ | 0.16 | 4.03 | 6.5E-5 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4813563 | chr20:25365340 | ENTPD6 | chr20:25176339-25207360:+ | 0.3 | 6.69 | 6.1E-11 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4813563 | chr20:25365340 | FAM182A | chr20:26035250-26067552:+ | 0.19 | 3.48 | 0.000547 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4813563 | chr20:25365340 | FAM182B | chr20:25744102-25848786:- | -0.26 | -5.44 | 8.47E-8 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4813563 | chr20:25365340 | NINL | chr20:25433338-25566153:- | 0.34 | 7.05 | 6.43E-12 | Liver enzyme levels (alkaline phosphatase) |
| THCA | cis | rs7267979 | 1 | rs4813563 | chr20:25365340 | PYGB | chr20:25228706-25278647:+ | 0.14 | 3.59 | 0.000363 | Liver enzyme levels (alkaline phosphatase) |